Journal Club May 16, 2006

Immunity. 2006 Mar;24(3):317-27.

Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1.

Sutterwala FS, Ogura Y, Szczepanik M, Lara-Tejero M, Lichtenberger GS, Grant EP, Bertin J, Coyle AJ, Galan JE, Askenase PW, Flavell RA.


Cancer Cell. 2006 Mar;9(3):157-73.

Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis.

Phillips HS, Kharbanda S, Chen R, Forrest WF, Soriano RH, Wu TD, Misra A, Nigro JM, Colman H, Soroceanu L, Williams PM, Modrusan Z, Feuerstein BG, Aldape K.


Cancer Cell. 2006 Mar;9(3):175-87.

The transcription factor MEF/ELF4 regulates the quiescence of primitive hematopoietic cells.

Lacorazza HD, Yamada T, Liu Y, Miyata Y, Sivina M, Nunes J, Nimer SD.


Cancer Cell. 2006 Apr;9(4):287-300.

Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain.

Sun L, Hui AM, Su Q, Vortmeyer A, Kotliarov Y, Pastorino S, Passaniti A, Menon J, Walling J, Bailey R, Rosenblum M, Mikkelsen T, Fine HA.


Cancer Res. 2006 Jan 1;66(1):159-67.

Distinct transcription profiles of primary and secondary glioblastoma subgroups.

Tso CL, Freije WA, Day A, Chen Z, Merriman B, Perlina A, Lee Y, Dia EQ, Yoshimoto K, Mischel PS, Liau LM, Cloughesy TF, Nelson SF.


Cancer Res. 2006 Jan 1;66(1):563-70.

Identification of the NKG2D haplotypes associated with natural cytotoxic activity of peripheral blood lymphocytes and cancer immunosurveillance.

Hayashi T, Imai K, Morishita Y, Hayashi I, Kusunoki Y, Nakachi K.


Cancer Res. 2006 Jan 15;66(2):803-11.

The possible role of EWS-Fli1 in evasion of senescence in Ewing family tumors.

Matsunobu T, Tanaka K, Nakamura T, Nakatani F, Sakimura R, Hanada M, Li X, Okada T, Oda Y, Tsuneyoshi M, Iwamoto Y.


Cancer Res. 2006 Jan 15;66(2):673-81.

c-myc overexpression causes anaplasia in medulloblastoma.

Stearns D, Chaudhry A, Abel TW, Burger PC, Dang CV, Eberhart CG.


Blood. 2006 Jan 1;107(1):106-10.

Runx1 function in hematopoiesis is required in cells that express Tek.

Li Z, Chen MJ, Stacy T, Speck NA.


Blood. 2006 Jan 1;107(1):197-204.

ZAP-70 expression in acute lymphoblastic leukemia: association with the E2A/PBX1 rearrangement and the pre-B stage of differentiation and prognostic implications.

Chiaretti S, Guarini A, De Propris MS, Tavolaro S, Intoppa S, Vitale A, Iacobelli S, Elia L, Ariola C, Ritz J, Foa R.


Blood. 2006 Jan 1;107(1):305-8.

Bmi-1 is useful as a novel molecular marker for predicting progression of myelodysplastic syndrome and patient prognosis.

Mihara K, Chowdhury M, Nakaju N, Hidani S, Ihara A, Hyodo H, Yasunaga S, Takihara Y, Kimura A.


Blood. 2006 Jan 1;107(1):358-66.

Total body irradiation selectively induces murine hematopoietic stem cell senescence.

Wang Y, Schulte BA, LaRue AC, Ogawa M, Zhou D.


Blood. 2006 Jan 15;107(2):492-500.

Expression of Pitx2 in stromal cells is required for normal hematopoiesis.

Kieusseian A, Chagraoui J, Kerdudo C, Mangeot PE, Gage PJ, Navarro N, Izac B, Uzan G, Forget BG, Dubart-Kupperschmitt A.


Blood. 2006 Apr 1;107(7):2643-52.

Differentiation of naive cord-blood T cells into CD19-specific cytolytic effectors for posttransplantation adoptive immunotherapy.

Serrano LM, Pfeiffer T, Olivares S, Numbenjapon T, Bennitt J, Kim D, Smith D, McNamara G, Al-Kadhimi Z, Rosenthal J, Forman SJ, Jensen MC, Cooper LJ.


Blood. 2006 Apr 1;107(7):2680-5.

Mutations in dyskeratosis congenita: their impact on telomere length and the diversity of clinical presentation.

Vulliamy TJ, Marrone A, Knight SW, Walne A, Mason PJ, Dokal I.


Blood. 2006 Apr 15;107(8):3131-7.

Human thymus contains multipotent progenitors with T/B lymphoid, myeloid, and erythroid lineage potential.

Weerkamp F, Baert MR, Brugman MH, Dik WA, de Haas EF, Visser TP, de Groot CJ, Wagemaker G, van Dongen JJ, Staal FJ.


Blood. 2006 Apr 15;107(8):3303-12.

AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1.

Nishida S, Hosen N, Shirakata T, Kanato K, Yanagihara M, Nakatsuka S, Hoshida Y, Nakazawa T, Harada Y, Tatsumi N, Tsuboi A, Kawakami M, Oka Y, Oji Y, Aozasa K, Kawase I, Sugiyama H.