Morning Seminar April 21, 2006

Transplantation for infants with acute leukemia.
Jean E. Sanders

The role of SCT for infants with either ALL or AML remains controversial.


Blood. 2004 Dec 1;104(12):3527-34. Epub 2004 Aug 5.

Infant acute lymphoblastic leukemia with MLL gene rearrangements: outcome following intensive chemotherapy and hematopoietic stem cell transplantation.

Kosaka Y, Koh K, Kinukawa N, Wakazono Y, Isoyama K, Oda T, Hayashi Y, Ohta S, Moritake H, Oda M, Nagatoshi Y, Kigasawa H, Ishida Y, Ohara A, Hanada R, Sako M, Sato T, Mizutani S, Horibe K, Ishii E.


J Clin Oncol. 2006 Jan 1;24(1):145-51.

Comparable long-term survival after unrelated and HLA-matched sibling donor hematopoietic stem cell transplantations for acute leukemia in children younger than 18 months.

Eapen M, Rubinstein P, Zhang MJ, Camitta BM, Stevens C, Cairo MS, Davies SM, Doyle JJ, Kurtzberg J, Pulsipher MA, Ortega JJ, Scaradavou A, Horowitz MM, Wagner JE.


Blood. 2005 May 1;105(9):3749-56.

Allogeneic hematopoietic cell transplantation for infants with acute lymphoblastic leukemia.

Sanders JE, Im HJ, Hoffmeister PA, Gooley TA, Woolfrey AE, Carpenter PA, Andrews RG, Bryant EM, Appelbaum FR.