Pediatric Hematology/Oncology (AREKEN) Osaka Univ Grad School Med

We are treating children with cancer and hematological disorder at Osaka University Hospital, Japan.
Contact us at areken@ped.med.osaka-u.ac.jp

Wednesday, October 25, 2006

Journal Club October 25, 2006

Cancer Research, April-September 2006

Brain-derived neurotrophic factor (BDNF) activation of TrkB induces vascular endothelial growth factor (VEGF) expression via hypoxia-inducible factor-1a (HIF-1a) in neuroblastoma cells
(Cancer Res 66: 4249, 2006)

Mirk/Dyrk1b mediates cell survival in rhabdomyosarcoma
(Cancer Res 66: 5143, 2006)

Keratoepithelin suppresses the progression of experimental human neuroblastoma
(Cancer Res 66: 5314, 2006)

Insulin-like growth factor-I receptor (IGF-IR) expression regulates neuroblastoma metastasis to bone
(Cancer Res 66: 6570, 2006)

Single-cell cloning of human, donor-derived antileukemia T-cell lines for in vitro separation of GVL effect from GVH reaction
(Cancer Res 66: 7310, 2006)

Early growth response gene-1 (Egr-1) regulates hypoxia-induced expression of tissue factor in glioblastma multiforme through hypoxia –inducible factor-1 (HIF-1)-independent mechanisms
(Cancer Res 66: 7067, 2006)

Identification of a PAX-FKHR gene expression signature that defines molecular classes and determines the prognosis of alveolar RMS
(Cnacer Res 66: 6936, 2006)

Expression of the FUS-CHOP fusion protein in primary mesenchymal progenitor cells gives rise to a model of myxoid liposarcoma
(Cancer Res 66: 7016, 2006)

Inhibition of PI3K destabilizes MycN protein and blocks malignant progression in neuroblastoma
(Cancer Res 66: 8139, 2006)


Blood, April 2006

Donor CD4+ T and B cells in transplants induce cGVHD with autoimmune manifestations
(Blood 107: 2993, 2006)

Natural gene therapy in monozygotic twins with Fanconi anemia
(Blood 107: 3084, 2006)


Correction of canine X-linked SCID by in vivo retroviral gene therapy
(Blood 107: 3091, 2006)

AML1-ETO rapidly induces AML in cooperation with WT1
(Blood 107: 3303, 2006)


Blood, July 2006

Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells
(Blood 108: 116, 2006)

HGF favors monocyte differentiation into regulatory IL-10++IL-12low/neg accessory cells with dendritic-cell features
(Blood 108: 218, 2006)

Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors
(Blood 108: 737, 2006)